_____ first, he could speak little English.

A. In    B. On    C. At    D. From

At first, he could speak little English.

参考译文：起初，他能说很少的英文。

答案解析C， at first 固定搭配，首先，刚开始

at first 起初，当初;首先

At first she threatened to dismiss us all, but later she relented.

起初她威胁要解雇我们所有的人，但是后来她态度软化了。

At first we didn't realized the severity of her wounds.

起初我们并没有意识到她的伤口的严重性。

Driving on the left is strange at first but you get used to it.

沿著路的左侧驾驶刚开始时有些别扭，可是习惯了就好了。

At first we used hand tools.

首先我们使用手工工具。

At first I really didn'tcare whether he came or not.  

起先我真的不在乎他是否会来。

At first, he was blissfully unaware of the conspiracy against him.  

起初，他幸好不知道那些针对他的阴谋。

At first I felt very resentful and angry about losing my job.  

起初我对丢掉工作感到非常怨恨和恼怒。